Types of presentation
Oral Presentation
Presentation time for ORAL presentation is 10 minutes + 5 min for questions from the audience.
You shall make your presentation in a timely manner. Kindly note that the time is usually followed the the conference Chairman.
All presentations have to be made in English
Speakers are kindly asked to use the available in the Conference hall Laptop. Only if they have special reasons they may use their own laptops (in that case they have to inform the technical assistant before the session).
Only PowerPoint presentations on a CD-ROM/DVD or a USB Memory stick will be accepted.
Types of presentation
Oral Presentation
Presentation time for ORAL presentation is 10 minutes + 5 min for questions from the audience.
You shall make your presentation in a timely manner. Kindly note that the time is usually followed the the conference Chairman.
All presentations have to be made in English
Speakers are kindly asked to use the available in the Conference hall Laptop. Only if they have special reasons they may use their own laptops (in that case they have to inform the technical assistant before the session).
Only PowerPoint presentations on a CD-ROM/DVD or a USB Memory stick will be accepted.
Types of presentation
Oral Presentation
Presentation time for ORAL presentation is 10 minutes + 5 min for questions from the audience.
You shall make your presentation in a timely manner. Kindly note that the time is usually followed the the conference Chairman.
All presentations have to be made in English
Speakers are kindly asked to use the available in the Conference hall Laptop. Only if they have special reasons they may use their own laptops (in that case they have to inform the technical assistant before the session).
Only PowerPoint presentations on a CD-ROM/DVD or a USB Memory stick will be accepted.
Types of presentation
Oral Presentation
Presentation time for ORAL presentation is 10 minutes + 5 min for questions from the audience.
You shall make your presentation in a timely manner. Kindly note that the time is usually followed the the conference Chairman.
All presentations have to be made in English
Speakers are kindly asked to use the available in the Conference hall Laptop. Only if they have special reasons they may use their own laptops (in that case they have to inform the technical assistant before the session).
Only PowerPoint presentations on a CD-ROM/DVD or a USB Memory stick will be accepted.
Publication ethics
Authors
The Author declares that the manuscript is original and in its present form has not been published elsewhere in any form, that it has not been submitted to any journal/proceedings and that it will not be submitted to any other journal/proceedings, if it is accepted for publication in the GEOLINKS Conference Proceedings.
The Author is responsible for the research they have been done and for the results described in the paper.
The Author warrants that the article doesn't infringe upon any copyright, contains no libelous or otherwise unlawful statements, and does not otherwise infringe on the rights of others.
The Author transfers the copyright for this publication/article to the GEOLINKS Conferences.
The Author licenses to the Publisher the right to distribute the Article as a part of GEOLINKS Conference proceedings.
Submission Guidelines
Abstract Submission
An abstract between 300 to 500 words, clearly summarising the arguments, should be submitted before deadline.
The preferred length of paper (including footnotes) is 5,000 words (maximum limit). In general, please confine your paper between 10-12 pages, everything included.
It is author's responsibility to ensure that all references and citations are correct, and that the contribution does not contain any material that infringes copyright, or is defamatory, obscene or otherwise unlawful or litigious. Please check GEOLINKS Tips.
Copyright in the article will remain jointly with the owner of the copyright and the Publisher. By submitting an article to the conference, the owner of the copyright grants the publisher with a license to publish the article. The author warrants that he is the owner of all rights of copyright in the article. Where the author subsequently publishes the article, the author is requested to acknowledge the article appeared in the conference proceedings.
The Author(s) will indemnify and defend the Publisher against any claim, demand or recovery against the Publisher by reason of any violation of any proprietary right or copyright, or because of any libellous or scandalous matter contained in the Manuscript.
The Publisher will have the right to edit the work for the original edition and for any revision, provided that the meaning of the text is not materially altered.
Submission Guidelines
Abstract Submission
An abstract between 300 to 500 words, clearly summarising the arguments, should be submitted before deadline.
The preferred length of paper (including footnotes) is 5,000 words (maximum limit). In general, please confine your paper between 10-12 pages, everything included.
It is author's responsibility to ensure that all references and citations are correct, and that the contribution does not contain any material that infringes copyright, or is defamatory, obscene or otherwise unlawful or litigious. Please check GEOLINKS Tips.
Copyright in the article will remain jointly with the owner of the copyright and the Publisher. By submitting an article to the conference, the owner of the copyright grants the publisher with a license to publish the article. The author warrants that he is the owner of all rights of copyright in the article. Where the author subsequently publishes the article, the author is requested to acknowledge the article appeared in the conference proceedings.
The Author(s) will indemnify and defend the Publisher against any claim, demand or recovery against the Publisher by reason of any violation of any proprietary right or copyright, or because of any libellous or scandalous matter contained in the Manuscript.
The Publisher will have the right to edit the work for the original edition and for any revision, provided that the meaning of the text is not materially altered.
Types of presentation
Types of presentation
Types of presentation
Types of presentation
Types of presentation
Types of presentation
Types of presentation
Types of presentation
Types of presentation
Types of presentation
Types of presentation
Types of presentation
Types of presentation
Types of presentation
Types of presentation
Proceedings 2020
All GEOLINKS 2020 participants get an online access to the full conference proceedings.
You can find the full digital books, including all accepted and published double blind peer-reviewed papers.

GEOLINKS Proceedings
Book 1 Volume 2
Air Pollution and Climate Change
Biotechnologies
Environmental Geology
Soil Science
Water Resources
GEOLINKS Proceedings
Book 2 Volume 2
Ecology and Environmental Studies
Environmental Economics
Green Buildings Technology and Materials
Green Design and Sustainable Architecture
GEOLINKS International Conference 2021, Book 1
BIOTECHNOLOGIES
DETERMINATION OF THE OPTIMAL CONCENTRATIONS OF PECTIN AND CALCIUM CHLORIDE FOR THE SYNTHESIS OF CHITOSAN-PECTIN MICROPARTICLES
Prof. Dr. Alla A. Krasnoshtanova, Anastasiya D. Bezyeva
ABSTRACT
The oral route of drug inclusion is the most convenient for the patient. In addition to ease of use, this method of drug inclusion has such advantages as non-invasiveness of inclusion, absence of complications during injection; comparative safety for the organism due to the passage of the active substance and auxiliary compounds through the gastrointestinal tract; the possibility of introducing larger doses of the drug at one time. However, despite the obvious advantages, the oral route of inclusion has a number of significant disadvantages that significantly limit its use for a number of drugs. Among them are: relatively slow therapeutic action of the drug with this route of inclusion; the aggressive effect of a number of drugs (for example, antibiotics) on the gastrointestinal tract; low bioavailability of a number of substances (especially high molecular weight hydrophilic compounds), caused by poor permeability of the intestinal epithelium for hydrophilic and large molecules, as well as enzymatic and chemical degradation of the active substance in the gastrointestinal tract.
There are various approaches used in the development of oral drug delivery systems. In particular, for the targeted delivery of drugs, it is proposed to use nano- and microcapsules with mucoadhesive properties. Among the polymers used for the synthesis of these microparticles, it is preferable to use pH-dependent, gelable biopolymers that change their structure depending on the acidity of the environment. Microcapsules obtained from compounds with the above properties are capable of protecting the active substance (or from the active substance) in the stomach environment and ensuring its release in the intestine. These properties are possessed by such polysaccharides as alginate, pectin, carrageenan, xylan, etc. The listed biopolymers are non-toxic, biocompatible, and biodegradable, which makes microparticles containing these polysaccharides promising as oral drug delivery systems. To impart mucoadhesive properties to nanoparticles, complexes of the listed polymers with chitosan are used.
In this research, pectin, a polysaccharide formed mainly by residues of galacturonic acid, was used as a structural polymer. The concentrations of substances in the initial solutions were selected that were optimal for the synthesis of microcapsules. The main parameters for evaluating the resulting microparticles were the size of the capsules (less than 1 μm for oral inclusion), the zeta-potential, showing the tendency of the microparticles to stick together, and the completeness of the binding of the microparticles to chitosan.
It was found that the optimal solutions for the synthesis of microparticles are: 15.7 ml of a solution of pectin 0.093% by weight, 3.3 ml of a solution of chitosan 0.07% by weight and 1.0 ml of a solution of CaCl2 20 mM. The diameter of the microparticles obtained by this method was 700-800 nm, and the value of their zetta-potential, equal to - (34 ± 3) mV, does not cross the particle adhesion threshold. It was also found that the synthesis of microparticles at these concentrations of calcium chloride provides the most complete binding of chitosan to their surface, which increases the mucoadhesive properties of microparticles.
KEYWORDS
pectin, chitosan, microparticles, sorption capacity