This study aimed to identification of some rootstocks for cucurbitaceous vegetables and their influence on cultures. These vegetables (cucumber, watermelon, melon) are very popular crops in Romania. Vegetable crops are very sensitive to climatic vagaries, so fluctuation in climatic parameters at any phase of growth can affect the yield. Grafting on Cucurbitaceae is a method which has improved and spread quickly during the past years, a similar approach to crop rotation, a practice meant to increase productivity, resistance or tolerance to soil diseases and pests, as well as to abiotic factors and at increasing fruit quality. The research was conducted at the Horting Institute, Bucharest, Romania. Several aspects are taken into account in the use of rootstocks: environmental adaptability, quality fruit, resistance/tolerance for soil diseases and pests, drought, floods, soil salinization, heavy metal content, organic pollutants. Some resistant rootstocks have been identified worldwide (PS1313, RS841, bottle-gourd, NUN-9075, Argentario, PI296341 and others). Several rootstocks are very used in Romania for conventional and ecological crops (UG 29A, Shintoza, Emphasis, Cobalt and others). Following the studies undertaken on research trials in the greenhouses, many rootstock genotypes were selected and tested in the Horting Institute and some results are presented in this paper.